Formaldehyde le glutaraldehydeka bobeli ke lisebelisoa tsa lik'hemik'hale tse sebelisoang e le lisebelisoa tse kopanyang lits'ebetsong tse fapaneng, haholo-holo mafapheng a baeloji, k'hemistri le mahlale a thepa.Le ha li sebeletsa merero e ts'oanang ho hokahanya limolek'hule tsa bioloji le ho boloka mehlala ea likokoana-hloko, li na le likarolo tse ikhethang tsa lik'hemik'hale, ts'ebetso, chefo, le ts'ebeliso.
Tse tšoanang:
Crosslinking Agents: Ka bobeli formaldehyde leglutaraldehyde ke aldehydes, ho bolelang hore ba na le sehlopha sa carbonyl (-CHO) qetellong ea sebopeho sa bona sa molek'hule.Mosebetsi oa bona o ka sehloohong ke ho theha maqhama a covalent pakeng tsa lihlopha tse sebetsang tsa li-biomolecules, e leng se fellang ka ho kopanya.Crosslinking ke ea bohlokoa bakeng sa ho tsitsisa sebopeho sa disampole tsa likokoana-hloko, ho etsa hore li be matla le ho hanyetsa ho senyeha.
Lisebelisoa tsa Biomedical: Ka bobeli formaldehyde le glutaraldehyde li fumana ts'ebeliso ea bohlokoa tšimong ea biomedical.Hangata li sebelisoa bakeng sa ho lokisa le ho boloka lithane ho lithuto tsa histology le pathology.Li-tissue tse kopantsoeng li boloka botšepehi ba tsona ba sebopeho 'me li ka tsoela pele ho sebetsoa bakeng sa merero e fapaneng ea tlhahlobo le tlhahlobo.
Taolo ea Likokoana-hloko: Ka bobeli li na le thepa e thibelang likokoana-hloko, e li etsang hore e be tsa bohlokoa ts'ebetsong ea ho bolaea likokoana-hloko le ho thibela likokoana-hloko.Li ka koala libaktheria, livaerase le li-fungus, tsa fokotsa kotsi ea tšoaetso libakeng tsa laboratori le lisebelisoa tsa bongaka.
Lisebelisoa tsa indasteri: Ka bobeli formaldehyde leglutaraldehydeli sebelisoa libakeng tse fapaneng tsa indasteri.Ba hiriloe ho etsa li-adhesives, resin le polymers, hammoho le indastering ea matlalo le ea masela.
Liphapang:
Sebopeho sa Lik'hemik'hale: Phapang e ka sehloohong pakeng tsa formaldehyde le glutaraldehyde e ka har'a likarolo tsa tsona tsa limolek'hule.Formaldehyde (CH2O) ke aldehyde e bonolo ka ho fetisisa, e entsoeng ka athomo e le 'ngoe ea carbon, liathomo tse peli tsa hydrogen le athomo e le' ngoe ea oksijene.Glutaraldehyde (C5H8O2), ka lehlakoreng le leng, ke aliphatic aldehyde e rarahaneng, e nang le liathomo tse hlano tsa carbon, liathomo tse robeli tsa hydrogen, le liathomo tse peli tsa oksijene.
Reactivity: Glutaraldehyde hangata e sebetsa ho feta formaldehyde ka lebaka la ketane ea eona e telele ea khabone.Ho ba teng ha liathomo tse hlano tsa carbon ho glutaraldehyde ho e lumella ho koala sebaka se selelele pakeng tsa lihlopha tse sebetsang ho li-biomolecules, e leng se lebisang ho crosslinking ka potlako le e sebetsang haholoanyane.
Katleho ea Crosslinking: Ka lebaka la ts'ebetso ea eona e phahameng, glutaraldehyde hangata e sebetsa hantle ho kopanya li-biomolecule tse kholoanyane, joalo ka liprotheine le li-enzyme.Formaldehyde, leha e ntse e khona ho hokahana, e ka hloka nako e eketsehileng kapa likhakanyo tse phahameng ho fihlela liphetho tse bapisoang le limolek'hule tse kholoanyane.
Chefo: Glutaraldehyde e tsejoa e le chefo ho feta formaldehyde.Ho pepesehela glutaraldehyde ka nako e telele kapa ho hoholo ho ka baka ho teneha ha letlalo le ho phefumoloha, 'me ho nkuoa e le sensitizer, ho bolelang hore e ka lebisa ho ts'oaetso ho batho ba bang.Ka lehlakoreng le leng, formaldehyde ke kankere e tsebahalang haholo 'me e baka likotsi tsa bophelo bo botle, haholo-holo ha motho a hema kapa a kopana le letlalo.
Lisebelisoa: Leha lik'hemik'hale ka bobeli li sebelisoa ho lokisa lisele, hangata li ratoa bakeng sa merero e fapaneng.Formaldehyde e atisa ho sebelisoa bakeng sa mekhoa e tloaelehileng ea histological le ho tlotsa setopo, ha glutaraldehyde e loketse haholoanyane ho boloka mehaho ea lisele le libaka tsa antigenic lithutong tsa electron microscopy le immunohistochemical.
Botsitso: Formaldehyde e fetoha mouoane haholo 'me e atisa ho fetoha mouoane ka potlako ho feta glutaraldehyde.Thepa ena e ka susumetsa litlhoko tsa ho ts'oaroa le ho boloka li-agent tsa crosslinking.
Ka bokhutšoanyane, formaldehyde le glutaraldehyde li arolelana litšobotsi tse tloaelehileng e le li-crosslinking agents, empa li fapane haholo ka mekhoa ea tsona ea lik'hemik'hale, ts'ebetso ea ts'ebetso, chefo le lisebelisoa.Kutloisiso e nepahetseng ea liphapang tsena ke ea bohlokoa bakeng sa ho khetha moemeli ea loketseng oa ho kopanya molemong oa merero e itseng le ho netefatsa ts'ebeliso e bolokehileng le e sebetsang maemong a fapaneng a saense, bongaka le indasteri.
Nako ea poso: Jul-28-2023