Ka tlase ke kenyelletso e khuts'oane mabapi le mekhoa ea ts'ebetso, mefuta le tlhahlobo ea li-preservatives tse fapaneng.
1.Mokhoa o akaretsang oa ts'ebetso eali-preservative
Li-preservative ke lisebelisoa tsa lik'hemik'hale tse thusang ho bolaea kapa ho thibela ts'ebetso ea likokoana-hloko ka har'a litlolo le ho boloka boleng ba litlolo ka nako e telele.
Leha ho le joalo, hoa lokela ho hlokomeloa hore li-preservative ha li bactericide 鈥 ha li na phello e matla ea bactericidal, 'me li sebetsa feela ha li sebelisoa ka bongata bo lekaneng kapa ha li kopana ka ho toba le likokoana-hloko.
Li-preservatives li thibela kholo ea likokoana-hloko li thibela ho qaptjoa ha li-enzyme tsa bohlokoa tsa metabolism hammoho le ho thibela motsoako oa liprotheine likarolong tsa bohlokoa tsa lisele kapa motsoako oa nucleic acid.
2.Lintlha tse amang Mesebetsi ea Li-Preservatives
Lintho tse ngata li tlatsetsa phello ea li-preservatives.Li kenyeletsa;
a.Phello ea pH
Phetoho ea pH e kenya letsoho ho qhaqhoeng ha li-preservatives tsa organic acid, 'me kahoo e ama katleho e akaretsang ea li-preservatives.Nka mohlala, pH 4 le pH 6, 2-bromo-2-nitro-1,3-propanediol e tsitsitse haholo.
b.Liphello tsa gel le likaroloana tse tiileng
Koalin, silicate ea magnesium, aluminium joalo-joalo, ke likaroloana tse ling tsa phofo tse teng ka har'a litlolo tse ling, tseo hangata li monyang li-preservative 'me kahoo li lebisa ho lahleheloa ke ts'ebetso ka ho boloka.Leha ho le joalo, tse ling li boetse li atleha ho monya libaktheria tse teng ka har’a sebolaya-mafu.Hape, motsoako oa li-polymer gel tse qhibilihang ka metsing le li-preservative li kenya letsoho ho fokotseheng ha li-preservative tse setseng tsa ho etsoa ha litlolo, 'me sena se boetse se fokotsa phello ea li-preservative.
c.Phello ea Solubilization ea li-nonionic surfactants
Ho kopanya ha li-surfactants tse fapaneng joalo ka li-surfactants tsa nonionic ho li-preservatives le hona ho ama ts'ebetso ea kakaretso ea li-preservative.Leha ho le joalo, li-nonionic surfactants tse qhibilihang ka oli tse kang HLB=3-6 li tsebahala li na le matla a holimo a ho tima li-preservatives ha li bapisoa le li-nonionic surfactants tse qhibilihang ka metsing tse nang le boleng bo holimo ba HLB.
d.Phello ea ho senyeha hoa ho boloka
Ho na le lintlha tse ling tse kang ho futhumatsa, leseli joalo-joalo, tse ikarabellang bakeng sa ho baka ho senyeha ha li-preservatives, ka hona ho baka ho fokotseha ha phello ea bona ea likokoana-hloko.Ho feta moo, tse ling tsa litlamorao tsena li lebisa karabelong ea biochemical ka lebaka la ho bola le mahlaseli a kotsi.
e.Mesebetsi e meng
Ka mokhoa o ts'oanang, lintlha tse ling tse kang ho ba teng ha litlolo le li-chelating agents le ho ajoa ha li-preservatives metsing a oli-metsi a mekhahlelo e 'meli le tsona li tla tlatsetsa ho fokotsa mosebetsi oa li-preservative ho isa tekanyong e itseng.
3.Thepa ea antiseptic ea li-preservatives
Lintho tse thibelang likokoana-hloko tsa li-preservative li lokela ho nahanoa.Ho ba le li-preservatives tse feteletseng ho litlolo ho tla etsa hore e tenehe, athe khaello ea mahloriso e tla ama sebolaya-mafu.litšobotsi tsa li-preservatives.Mokhoa o motle oa ho lekola sena ke ho sebelisa tlhahlobo ea phephetso ea baeloji e kenyelletsang bonyane ba inhibitory concentration (MIC) le tlhahlobo ea sebaka sa inhibition.
Teko ea "Bacteriostatic Circle": Teko ena e sebelisoa ho fumana libaktheria le hlobo tse nang le bokhoni ba ho hola kapele ka mor'a ho lema sebakeng se loketseng.Boemong boo ho eona "filter paper disc" e kentsoeng ka "preservative" e theoleloa bohareng ba poleiti e bohareng ea setso, ho tla ba le selikalikoe sa bacteriostatic se thehiloeng ho pota-pota ka lebaka la ho kenella ha li-preservative.Ha o metha bophara ba selika-likoe sa bacteriostatic, e ka sebelisoa e le lesela ho fumana hore na sebapali se sebetsa joang.
Ka sena, ho ka boleloa hore selikalikoe sa bacteriostatic se sebelisang mokhoa oa pampiri ka bophara> = 1.0mm se sebetsa haholo.MIC e bitsoa "preservative" e fokolang haholo e ka kenyelletsoang ka har'a mokhoa oa ho thibela kholo ea likokoana-hloko.Boemong bo joalo, MIC e nyane, e matlafatsa thepa ea antimicrobial ea preservative.
Matla kapa phello ea ts'ebetso ea antimicrobial hangata e hlahisoa ka mokhoa oa bonyane ba inhibitory concentration (MIC).Ka ho etsa joalo, tšebetso e matla ea antimicrobial e khethoa ke boleng bo bonyenyane ba MIC.Leha MIC e ke ke ea sebelisoa ho khetholla lipakeng tsa tšebetso ea bactericidal le bacteriostatic, li-surfactants ka kakaretso li tsejoa li na le phello ea bacteriostatic maemong a tlase le phello ea ho thibela likokoana-hloko maemong a holimo.
Ha e le hantle, ka linako tse fapaneng, mesebetsi ena e 'meli e etsahala ka nako e le' ngoe, 'me sena se etsa hore ho be thata ho aroloa.Ka lebaka lena, hangata ba fuoa lebitso le kopaneng e le antimicrobial disinfection kapa feela ho bolaea likokoana-hloko.
Nako ea poso: Jun-10-2021