Triclosanke sebolaya dikokwana-hloko tse pharalletseng tse sebediswang e le sebolaya dikokwana-hloko, sebolaya dikokwana-hloko kapa se sireletsang maemong a kliniki, dihlahiswa tse fapaneng tsa bareki ho kenyeletswa ditlolo, dihlahiswa tsa ho hlwekisa ka tlung, disebediswa tsa polasetiki, dibapadiswa, dipente, jj. masela, lisebelisoa tsa kichineng, joalo-joalo, tseo e ka 'nang ea theoha butle ka nako e telele nakong ea ts'ebeliso ea tsona, ho etsa ketso ea eona ea biocidal.
triclosan e sebelisoa joang litlolong?
TriclosanE thathamisitsoe ho 1986 ho European Community Cosmetics Directive hore e sebelisoe e le se sireletsang lihlahisoa tsa litlolo ka likhakanyo tse fihlang ho 0.3%.Tlhahlobo ea kotsi ea morao-rao e entsoeng ke Komiti ea Saense ea EU ea Lihlahisoa tsa Bareki e fihletse qeto ea hore, le hoja tšebeliso ea eona ka tekanyo e phahameng ea 0.3% ea sesepa sa meno, sesepa sa letsoho, sesepa sa 'mele / li-gels tsa shaoara le lithupa tse nkhang hamonate li ne li nkoa li sireletsehile sebakeng sa chefo. lihlahisoa tsa motho ka mong, boholo ba ho pepeseha ka kakaretso ho triclosan ho tsoa lihlahisoa tsohle tsa litlolo ha bo bolokehe.
Tšebeliso leha e le efe e eketsehileng ea triclosan ka phofo ea sefahleho le ho pata sekoli sebakeng sena le eona e ne e nkoa e sireletsehile, empa tšebeliso ea triclosan lihlahisoa tse ling tsa ho tlohela (mohlala, litlolo tsa 'mele) le ho hlatsoa molomo ha lia ka tsa nkoa li sireletsehile bakeng sa bareki ka lebaka la ho ba le phello e phahameng. exposure/Ho pepesetsoa ha triclosan ho tsoa lihlahisoa tsa spray (mohlala, li-deodorants) ha lia hlahlojoa.
TriclosanKaha ha e na ionic, e ka etsoa ka li-dentifrices tse tloaelehileng.Leha ho le joalo, ha e tlamelle holim'a libaka tsa molomo ka nako e fetang lihora tse 'maloa, ka hona ha e fane ka boemo bo tsitsitseng ba ts'ebetso ea anti-plaque.Ho eketsa ho kenngoa le ho boloka triclosan ka holim'a molomo bakeng sa ntlafatso ea taolo ea plaque le bophelo bo botle ba gingival, triclosan / polyvinylmethyl ether maleic acid copolymer le triclosan / zinc citrate le triclosan / calcium carbonate dentifrice li sebelisoa.
triclosan e sebelisoa joang ho tsa bophelo bo botle le lisebelisoa tsa bongaka?
Triclosane 'nile ea sebelisoa ka katleho ho tsa bongaka ho felisa likokoana-hloko tse kang methicillin-resistant Staphylococcus aureus (MRSA), haholo-holo ka tlhahiso ea ho sebelisa 2% ea triclosan bath.Triclosan e sebelisoa e le lisebelisoa tsa ho buoa, 'me e sebelisoa haholo ho hlapa matsoho le ho hlatsoa 'mele ho felisa MRSA ho bajari pele ho opereishene.
Triclosan e sebelisoa lisebelisoeng tse 'maloa tsa bongaka, mohlala li-stents tsa ureteral, sutures ea ho buuoa 'me e ka nkoa e le ho thibela tšoaetso ea graft.Bojar et al ha baa ka ba bona phapang pakeng tsa bokolone pakeng tsa sutures e entsoeng ka triclosan le suture e tloaelehileng ea multifilament, le hoja mosebetsi oa bona o ne o ama libaktheria tse hlano 'me o itšetlehile feela ka boikemisetso ba sebaka sa ho thibela.
Li-stents tsa ureteral, triclosan e bontšitsoe ho thibela ho hōla ha likokoana-hloko tse tloaelehileng tsa uropathogens le ho fokotsa ts'oaetso ea tšoaetso ea moroto 'me, mohlomong, ho kenngoa ha catheter ho sa tsoa bontša liphello tsa synergistic tsa triclosan le lithibela-mafu tse amehang lihlopheng tsa bongaka tse nang le mefuta e supileng ea uropathogenic. 'me li tšehetsa tšebeliso ea triclosan-eluting stent ha ho hlokahala, hammoho le phekolo e tloaelehileng ea lithibela-mafu ha ho phekoloa bakuli ba rarahaneng.
Lintlafatsong tse ling, tšebeliso ea triclosan ka har'a catheter ea Foley e ile ea khothaletsoa kaha triclosan e atlehile ho thibela ho hola ha Proteus mirabilis le ho thibela ho koaloa ha catheter.Haufinyane tjena, Daruiche et al.e bontšitse ts'ebetso e ts'oanang, e pharaletseng le e tšoarellang ea antimicrobial ea li-catheters tse koahetsoeng ka motsoako oa triclosan le DispersinB, e leng enzyme e thibelang likokoana-hloko e thibelang le ho qhalakanya biofilm.
triclosan e sebelisoa joang lihlahisoa tse ling tsa bareki?
Ts'ebetso ea antimicrobial e pharalletseng ea triclosan e lebisitse ho kenyelletsoeng ha eona lethathamong le lelelele la lihlahisoa tsa lihlahisoa tse reretsoeng ho sebelisoa lapeng joalo ka sesepa sa metsi, li-detergents, liboto tsa ho chora, lintho tsa ho bapala tsa bana, lik'hapete le lijana tsa polokelo ea lijo.Lethathamo le qaqileng la lihlahisoa tsa bareki tse nang le triclosan le fanoa ke US Environmental Protection Agency (EPA) le mekhatlo e ikemetseng ea US "Environmental Working Group" le "Beyond Pesticides" .
Palo e ntseng e eketseha ea thepa ea liaparo e phekoloa ka li-biocides.Triclosan ke e 'ngoe ea lisebelisoa tsa ho qetela bakeng sa tlhahiso ea masela a joalo .Masela a phethiloeng ka triclosan a tšoaroa ka li-cross-linking agents ho fana ka thepa ea antibacteria e tšoarellang.Motheong oa tlhaiso-leseling e fumanehang, lihlahisoa tse 17 tse tsoang 'marakeng oa mabenkele oa Danish li ile tsa sekasekoa bakeng sa litaba tsa metsoako e meng e khethiloeng ea antibacterial: triclosan, dichlorophen, Kathon 893, hexachlorophen, triclocarban le Kathon CG.Lihlahisoa tse hlano li fumanoe li na le 0.0007% - 0.0195% triclosan .
Aiello et al tlhahlobisong ea pele e hlophisitsoeng e hlahlobang molemo oa lisepa tse nang le triclosan, o ile a hlahloba lithuto tse 27 tse hatisitsoeng pakeng tsa 1980 le 2006. E 'ngoe ea liphuputso tsa bohlokoa ke hore lisepa tse neng li e-na le ka tlaase ho 1% triclosan li bontšitse hore ha li na molemo ho tsoa lisepeng tse sa sebeliseng likokoana-hloko.Lithuto tse sebelisitseng sesepa se nang le > 1% triclosan li bontšitse phokotso e kholo ea maemo a baktheria letsohong, hangata ka mor'a lits'ebetso tse ngata.
Ho bonahala ho haella ha kamano pakeng tsa tšebeliso ea sesepa e nang le triclosan le phokotso ea mafu a tšoaetsanoang ho ne ho le thata ho tsebahatsa ho ne ho le sieo ho tsebahatsoa ha lintho tsa tlhaho tse ikarabellang bakeng sa matšoao a bokuli.Liphuputso tse peli tsa morao-rao tsa US li bonts'itse hore ho hlapa matsoho ka sesepa se thibelang likokoana-hloko se nang le triclosan (0.46%) se fokolitse bongata ba baktheria le phetisetso ea libaktheria matsohong, ha ho bapisoa le ho hlatsoa matsoho ka sesepa se seng se thibelang likokoana-hloko.
Lihlahisoa tsa Selemo
Re hlahisa mefuta e mengata ea lihlahisoa tse ka sebelisoang indastering ea tlhokomelo ea botho le ea litlolo, joalo ka tlhokomelo ea letlalo, tlhokomelo ea moriri, tlhokomelo ea molomo, litlolo, ho hloekisa ka tlung, ho hloekisa le ho hlatsoa liaparo, ho hloekisa sepetlele le mekhatlo ea sechaba.Ikopanye le rona hona joale haeba u batla molekane ea tšepahalang oa khoebo.
Nako ea poso: Jun-10-2021