Joalo ka "aliphatic dibasic aldehyde" e tletseng ketane e otlolohileng, glutaraldehyde ke mokelikeli o pepeneneng o se nang 'mala o monko o khopisang le phello e ntle ea polao ho libaktheria tsa pelehi, livaerase, mycobacteria, hlobo ea pathogenic le baktheria ea baktheria, le bactericide e senang oxidizing e pharaletseng.Glutaraldehyde ke sebolaea-mafu se sebetsang hantle haholo se bolaeang mefuta e fapaneng ea likokoana-hloko 'me e khothaletsoa ke Mokhatlo oa Lefatše oa Bophelo e le sebolaea-mafu bakeng sa likokoana-hloko tsa lefu la sebete.
Glutaraldehyde 25%e na le litlamorao tse hlasimollang le tse folisang letlalong la motho le lera la motho 'me e ka baka ho kula, kahoo ha ea lokela ho sebelisoa bakeng sa ho bolaea likokoana-hloko moeeng le lisebelisoa tsa lijo.Ntle le moo, glutaraldehyde ha ea lokela ho sebelisoa bakeng sa ho bolaea likokoana-hloko le ho etsa sterilization ea lisebelisoa tsa bongaka tsa tubular, linale tsa ente, sutures ea opereishene le likhoele tsa k'hothone.
Glutaraldehyde e atisa ho sebelisoa e le sebolaya-mafu indastering ea bongaka 'me basebelisi ba ka ba le lipotso tse amanang le litaba tsa tekheniki, kahoo Springchem mona e fana ka lintlha tse kholo mabapi le glutaraldehyde bakeng sa referense ea hau.
Atlhahiso ea glutaraldehyde
Glutaraldehyde e sebelisoa e le sebolaea-mohatsela se batang ho bolaea likokoana-hloko lisebelisoa tse sa utloeleng mocheso, joalo ka li-endoscope le lisebelisoa tsa dialysis.E sebelisoa e le sebolaea likokoana-hloko sa boemo bo holimo bakeng sa lisebelisoa tseo tsa ho buoa tse ke keng tsa hloekisoa mocheso.
Glutaraldehyde e sebelisoa bakeng sa lits'ebetso tse 'maloa litsing tsa tlhokomelo ea bophelo:
● Sesebelisuoa sa ho lokisa lisele ka laboratoring ea mafu
● Sebolaea likokoana-hloko le ho hloekisa bokaholimo le lisebelisoa
● Mochine o thatafatsang o sebelisetsoang ho etsa X-ray
● Bakeng sa ho lokisa li-grafts
Ho felloa ke nakoletsatsi la glutaraldehyde le mokhoa oa ho tseba ho felloa ke nako
Mocheso oa kamore le tlas'a boemo ba ho ba hōle le polokelo e khanyang le e tiisitsoeng, letsatsi la ho fela ha glutaraldehyde ha lea lokela ho ba ka tlase ho lilemo tse 2, 'me karolo e sebetsang ea glutaraldehyde e lokela ho ba bonyane 2.0% nakong ea ho fela.
Mocheso oa kamore, ka mor'a ho eketsa rust inhibitor le pH adjuster, glutaraldehyde e sebelisoa bakeng sa sesebelisoa sa bongaka sa ho qoelisa sebolaea likokoana-hloko kapa sterilization, 'me se ka sebelisoa matsatsi a 14 a tsoelang pele.Likahare tsa glutaraldehyde li lokela ho ba bonyane 1.8% nakong ea tšebeliso.
Ho qoelisoa metsingdtšoaetsomokhoae nang le glutaraldehyde
Koahela lisebelisoa tse hloekisitsoeng ka 2.0% ~ 2.5% glutaraldehyde disinfection solution ho li qoelisa ka ho feletseng, ebe u koahela sejana se nang le likokoana-hloko mocheso oa kamore bakeng sa 60 min, 'me u hlatsoe ka metsi a sa hloekang pele u sebelisoa.
Lisebelisoa tse hloekisitsoeng le tse omisitsoeng tsa ho hlahloba le ho phekola, lisebelisoa le lingoliloeng li kenngoa ka har'a tharollo ea 2% ea alkaline glutaraldehyde e qoelisoang ka ho feletseng, 'me li-bubble tsa moea tse holim'a lisebelisoa li lokela ho tlosoa ka setshelo se koahetsoeng ka mocheso oa 20 ~ 25 ℃.Disinfection e sebetsa ho fihlela nako e behiloeng ea litaelo tsa sehlahisoa.
Litlhoko tsa ho thibela likokoana-hloko tsa endoscopes ka glutaraldehyde
1. Boemo bo phahameng ba ho thibela likokoana-hloko le litekanyetso tsa ho thibela likokoana-hloko
● Ho tsepamisa maikutlo: ≥2% (alkaline)
● Nako: bronchoscopy disinfection qoelisoa nako ≥ 20min;li-endoscopes tse ling ho thibela likokoana-hloko ≥ 10min;ho qoelisoa endoscopic bakeng sa bakuli ba nang le lefuba la mycobacterium, mycobacteria tse ling le mafu a mang a khethehileng ≥ 45min;sterilization ≥ 10h
2. Sebelisa mokhoa
● Mochine oa ho hloekisa le oa ho bolaea likokoana-hloko
● Ts'ebetso ea letsoho: sebolaya-mafu se lokela ho tlatsoa ka phaephe e 'ngoe le e 'ngoe ebe e kolobisoa ho thibela likokoana-hloko
3. Litlhokomelo
Glutaraldehyde 25%ke allergenic ebile e halefisa letlalo, mahlo le phefumoloho, 'me e ka baka dermatitis, conjunctivitis, ho ruruha ha nko le asthma ea mosebetsi, kahoo e lokela ho sebelisoa ho hloekisa endoscope le mochine oa ho thibela likokoana-hloko.
Litlhokomelo ka glutaraldehyde
Glutaraldehyde e halefisa letlalo le lera la mucous le chefo ho batho, 'me tharollo ea glutaraldehyde e ka baka tšenyo e tebileng mahlong.Ka hona, e lokela ho lokisoa le ho sebelisoa sebakeng se nang le moea o motle, tšireletso ea botho e lokela ho lokisoa hantle, e kang ho roala maske a sireletsang, liatlana tse sireletsang le likhalase tse sireletsang.Haeba e kopane le bona ka phoso, e lokela ho hlatsuoa hang-hang le ka ho tsoelang pele ka metsi, ’me ho lokela ho batloa tlhokomelo ea bongaka kapele haeba mahlo a lemetse.
E lokela ho sebelisoa sebakeng se nang le moea o motle, 'me haeba ho hlokahala, sebaka seo se lokela ho ba le lisebelisoa tsa ho ntša metsi.Haeba khatello ea glutaraldehyde moeeng sebakeng seo e sebelisoang e le holimo haholo, ho kgothaletswa ho ba le lisebelisoa tsa ho phefumoloha tse ikemetseng (mask e sireletsang khatello e ntle).Lijana tse sebelisoang bakeng sa lisebelisoa tsa ho inela li tlameha ho hloeka, li koaheloe li be li hlatsoe ka likokoana-hloko pele li sebelisoa.
Ho lekola khafetsa khatello ea glutaraldehyde
Khokahano e sebetsang ea glutaraldehyde e ka hlahlojoa ka likhoele tsa tlhahlobo ea lik'hemik'hale.
Ts'ebetsong e tsoelang pele, ts'ebeliso ea letsatsi le letsatsi e lokela ho matlafatsoa ho utloisisa liphetoho tsa eona tsa mahloriso, 'me ha ea lokela ho sebelisoa hang ha mahloriso a eona a fumanoa ka tlase ho khatello e hlokahalang.
Ho lokela ho netefatsoe hore khatello ea glutaraldehyde e sebelisoang e kopana le litlhoko tsa buka ea sehlahisoa.
Lokelaglutaraldehyde e kenngoe tšebetsong pele e sebelisoa?
Tharollo e nang le metsi ea glutaraldehyde e na le asiti 'me hangata ha e khone ho bolaea li-spores tse ntseng li hlaha ha li le acidic.Ke feela ha tharollo e "sebelisoa" ke alkalinity ho boleng ba pH ba 7.5-8.5 moo e ka bolaeang li-spores.Ha li se li kentsoe tšebetsong, litharollo tsena li na le nako ea ho phela bonyane matsatsi a 14.Maemong a alkaline pH, limolek'hule tsa glutaraldehyde li atisa ho polymerize.Polymerization ea glutaraldehyde e fella ka ho koaloa ha sebaka se sebetsang sa aldehyde sehlopha sa molek'hule ea eona ea glutaraldehyde e ikarabellang bakeng sa ho bolaea li-spores tse thunyang, ka hona phello ea bactericidal ea fokotseha.
Lintho tse amang sterilization ea glutaraldehyde
1. Nako ea ho tsepamisa maikutlo le ho nka khato
Phello ea bactericidal e tla ntlafatsoa ka ho eketseha ha mahloriso le katoloso ea nako ea ketso.Leha ho le joalo, tharollo ea glutaraldehyde e nang le karolo e boima ea karolo e ka tlaase ho 2% e ke ke ea finyella phello e ka tšeptjoang ea bactericidal ho likokoana-hloko tsa baktheria, ho sa tsotellehe hore na u ka atolosa nako ea bactericidal joang.Ka hona, hoa hlokahala ho sebelisa tharollo ea glutaraldehyde e nang le karolo e kholo ho feta 2% ho bolaea likokoana-hloko tsa baktheria.
2. Tharollo ea acidity le alkalinity
Tšusumetso ea bactericidal ea acid glutaraldehyde e tlase haholo ho feta ea alkaline glutaraldehyde, empa phapang e tla fokotseha butle-butle ka mocheso o ntseng o eketseha.Boemong ba pH 4.0-9.0, phello ea bactericidal e eketseha ka pH e ntseng e eketseha;phello e matla ea bactericidal e bonoa ho pH 7.5-8.5;ho pH> 9, glutaraldehyde e polima ka potlako mme phello ea bactericidal e lahleha ka potlako.
3. Mocheso
E boetse e na le phello ea bactericidal ka mocheso o tlase.Phello ea bactericidal ea glutaraldehyde e eketseha ka mocheso, 'me mocheso oa eona oa mocheso (Q10) ke 1.5 ho 4.0 ho 20-60 ℃.
4. Lintho tse phelang
Lintho tse phelang li etsa hore phello ea bactericidal e fokole, empa phello ea lintho tse phelang ho phello ea bactericidal ea glutaraldehyde e nyenyane ho feta ea likokoana-hloko tse ling.20% ea serum ea namane le 1% ea mali a felletseng ha e na phello ho phello ea bactericidal ea 2% glutaraldehyde.
5. Tšusumetso ea Synergistic ea li-surfactants tsa nonionic le lintlha tse ling tsa physicochemical
Polyoxyethylene fatty alcohol ether ke nonionic surfactant, 'me botsitso le phello ea bactericidal e ntlafatsoa haholo ka ho eketsa 0.25% polyoxyethylene e mafura ea joala ether ho tharollo ea glutaraldehyde e entsoeng ka glutaraldehyde e ntlafalitsoeng ea acid-base.Ultrasound, mahlaseli a hole a infrared le glutaraldehyde li na le phello ea synergistic sterilization.
Springchem, moetsi oa China ea holimo ho 10 oa glutaraldehyde, o fana ka glutaraldehyde 25% le 50% bakeng sa indasteri, laboratori, temo, bongaka, le merero e meng ea malapa, haholo-holo bakeng sa ho bolaea likokoana-hloko le ho bolaea libaka le lisebelisoa.Bakeng sa lintlha tse ling, ikopanye le rona feela.
Nako ea poso: Aug-16-2022